There's an article in this week's New Yorker about people who are attempting to breed domestic cats that look like ocelots, jaguars, and tigers: http://www.newyorker.com/reporting/2013/05/06/130506fa_fact_levy
Their aim is paradoxical: to come up with an animal that looks like it just walked out of the jungle before jumping up on your lap. This is not an easy task, and many "mistakes," both physical and temperamental, are born in the process.
For the moment, I am free from this obsession. I like a fluffy, cuddly-looking cat, because I am well aware of the wildness that lurks inside. What about you?